Calculate difference from a reference row in pandas (python) -


in pandas have data frame of type:

                       value samplegroup   sample               group1        ref      18.1               smp1     nan               smp2     20.3               smp3     30.0               smp4     23.8               smp5     23.2

what want do add new column reference (ref) has been subtracted samples (smp). this:

                       value   deltavalue samplegroup   sample               group1        ref      18.1    0               smp1     nan     nan               smp2     20.3    2.2               smp3     30.0    11.9               smp4     23.8    5.7               smp5     23.2    5.1

does know how can done? thanks!

ok knocked following worked me:

in [327]:  t="""sample value ref      18.1               smp1     nan               smp2     20.3               smp3     30.0               smp4     23.8               smp5     23.2""" df = pd.read_csv(io.stringio(t), sep='\s+') df out[327]:   sample  value 0    ref   18.1 1   smp1    nan 2   smp2   20.3 3   smp3   30.0 4   smp4   23.8 5   smp5   23.2 in [328]:  df['group'] = 'group1' df out[328]:   sample  value   group 0    ref   18.1  group1 1   smp1    nan  group1 2   smp2   20.3  group1 3   smp3   30.0  group1 4   smp4   23.8  group1 5   smp5   23.2  group1 in [329]:  df1 = df.set_index(['group', 'sample']) df1 out[329]:                value group  sample        group1 ref      18.1        smp1      nan        smp2     20.3        smp3     30.0        smp4     23.8        smp5     23.2  in [337]:  df1['deltavalue'] = df1['value'].sub(df1.loc[('group1','ref')]['value']) df1 out[337]:                value  deltavalue group  sample                    group1 ref      18.1         0.0        smp1      nan         nan        smp2     20.3         2.2        smp3     30.0        11.9        smp4     23.8         5.7        smp5     23.2         5.1

also following worked:

df1['deltavalue'] = df1['value'] - df1.loc[('group1','ref')]['value']

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